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The LLVLC Show (Episode 429): ‘Encore Week’ 2011 Interview With Dr. Robert Lustig

1-9-10 UPDATE: This post has been updated with the correct links to listen to the podcast on our brand new server. I apologize for the slow downloads the past week…everything seems to be working well now. THANK YOU!

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HAPPY NEW YEAR and I’m happy to bring you fresh podcast episodes to kick off your 2011 with a bang this week featuring the best of the best interview guests from 2010 with brand new conversations for you to enjoy during “Encore Week” 2011. In Episode 429 of “The Livin’ La Vida Low-Carb Show with Jimmy Moore,” we begin with the man who was initially reluctant to come on my show since he claims he “doesn’t believe in the low-carb lifestyle per se.” But after some cajoling from my fellow health podcaster Sean Croxton and others that my show is about so much more than a simple discussion of low-carb diets, Dr. Robert Lustig from “Sugar: The Bitter Truth” infamy agreed to come on for an interview. And a funny thing happened along the way–my conversation with him went on to become the #1 most-listened-to podcast interview of 2010 on “The Livin’ La Vida Low-Carb Show”–nearly DOUBLE the next closest interview that I did with Gary Taubes. WOW! And this is why I continued to pursue the interview even after Dr. Lustig initially declined. Aren’t you glad I didn’t give up on it?

Well, Dr. Lustig was overwhelmingly voted back for a brand new interview as one of the best of the best of 2010 as voted on by my listeners. And in this “Encore Week” follow-up to our July 2010 interview, he did not disappoint! Listen to Dr. Lustig talk about his view of a low-carb diet and why he is so hesitant to embrace it as a nutritional approach for most people, his personal experience following a low-carb diet, how he matches his patients to the lifestyle change that’s right for them, why he believes in the “safe carb,” high-fiber diet instead, what he thinks about the work of Gary Taubes and the one major difference between what they believe nutritionally, why we should eat fiber or sugar at all rather than mixing them, the four reasons why he promotes fiber so heavily, how our Paleolithic ancestors were able to consume upwards of 100-300 grams of fiber in their diet, the leptin sensitivity of knockout mice used in research, which is more important–leptin or insulin?, why high insulin levels block leptin, why weight gain is necessary during puberty and pregnancy, why he could extrapolate a conclusion from his pilot study of 44 people when only 8 of them experienced the benefit (and his follow-up double-blind, randomized, controlled trial), what he thinks about the recent research connecting fructose with pancreatic cancer, whether giving up fructose alone is enough to get rid of excess fat accumulation, the two “antidotes” to fructose that he believes can neutralize its impact, why being obese doesn’t necessarily mean your unhealthy, why he believes in personalized obesity treatment, what he thinks about whole grains (not “pulverized” grains) that do not contain fructose, why the liver is the primary target of insulin action from the pancreas, what he thinks about the change in name from HFCS to “corn sugar,” why the sugar industry is getting away with promoting sugar as harmless, and the death threats he has received from sugar proponents. Dr. Robert Lustig is a very articulate champion of many of the concepts we believe in and I’m grateful he agreed to come back again for another interview during “Encore Week” 2011.

There are three ways you can listen to Episode 429:

1. Listen at the iTunes page for the podcast:

2. Listen and comment about the show at the official web site for the podcast:

3. Download the MP3 file of Episode 429 [49:12m]:

THANK YOU SO MUCH FOR FINANCIALLY SUPPORTING THIS PODCAST! If these twice-weekly podcast interviews from the most provocative and thought-provoking diet, fitness, and health experts have helped you in any way over the past few months and years, then help us keep it going by clicking on the DONATE button on the official podcast web site. We love making these exclusive interviews available to you at no charge so that the positive low-carb message can get out there to the people who need to hear it the most. We are so grateful for your generous donations of any amount so we can keep this going all throughout 2010 and well beyond. I have a fantastic group of fresh new expert interview guests lined up for your listening enjoyment and can’t wait for you to hear them! Go to PayPal.com and you can give your gift to the e-mail address livinlowcarbman@charter.net. Your continued financial support and listenership is essential and we THANK YOU so very much for your support!

How did you like what you heard from Dr. Robert Lustig answering the questions from your fellow listeners? Tell us what you thought about what he shared in the show notes section of Episode 429. Check out Dr. Lustig’s “Sugar: The Bitter Truth” lecture and listen to my July 2010 interview to see why he was invited back for this special “Encore Week” interview. We’re loaded for bear the rest of the week with amazing interviews coming up from Denise Minger, Chris Masterjohn, Dr. Kurt Harris and Robb Wolf. It’s gonna be a fun week, so I hope you don’t miss a single show! THANK YOU FOR LISTENING!

If you have something to share about what you heard on “The Livin’ La Vida Low-Carb Show,” then drop us an e-mail at our dedicated podcast e-mail address–LLVLCShow@gmail.com. We’d love to hear from you about what you think about the show, interview guest suggestions (although keep in mind I’m fully booked up through May 2011), show topics, and anything else you want to share!

The official grand opening of “The Livin’ La Vida Low-Carb Show Fan Club” has arrived! Get special behind-the-scenes access to your favorite podcast, including the highly-coveted transcripts of past interviews, audio snippets of upcoming podcasts, see who I have scheduled for interviews and the ability to have me ask them YOUR questions, and so much more! It’s exclusive material for you uber-fans of “The Livin’ La Vida Low-Carb Show” and I appreciate your support of my work. SIGN UP TODAY!

  • Nina

    You are so cool. How did you manage to seduce Dr Lustig after initial reluctance? You sweet talking broadcaster you. Great work.

    Nina

    • http://www.livinlavidalowcarb.com Jimmy Moore

      Yes, it was my sultry powers of seduction. :D

  • http://ieatmostlymeat.com/ Josh

    Great podcast Jimmy. It sounds like Dr Lustig is more open to a lower carb diet then he was last time you interviewed him.

    • http://www.livinlavidalowcarb.com Jimmy Moore

      Slowly but surely Josh.

  • Peter Silverman

    It seems like the concept of “safe carbs” is increasingly going around. (Paul Jaminet is another person who uses it.). The question I have about safe carbs is: If a carb causes your sugar to spike, is it unsafe? A different way to put it is, is my $8 Wal-mart glucometer a good gude to which carbs are good for me.

    I ask, because I notice that whole grain rice causes my blood sugar to spike, as do black beans, and these are my favorite foods which I gave up. It sounds, from listening to Lustig, he thinks whole grains don’t cause people’s blood sugar to spike, but what about if they do.

    I wonder if Lustig and other scientists that are used to only talking to scientists, could learn to avoid in an interview using words that 99% of us listeners don’t understand, or if you should translate for them when they can’t.

    Thanks for these wonderful interviews this week.

    • http://www.livinlavidalowcarb.com Jimmy Moore

      Thanks Peter and I agree. That was the gist of what I was getting at with Lustig is that maybe for some of us that extra carb cutting is necessary.

    • Natalie

      According to Weston Price publications, whole grains have to be fermented to get rid of the phytic acid before they can safe for use. I don’t know if it’s true, but considering that every culture has done it traditionally, there must be something behind it. Personally, I think whole grains are fine if you’re in the maintenance mode and if you don’t overdo them. That said, I’ve cut them out completely for now when I’m trying to lose weight with the low carb.

      • http://www.livinlavidalowcarb.com Jimmy Moore

        Listen to the rest of my interviews this week for more on this subject, Natalie. THANKS for your comments!

  • Nina

    Oh but he DID. Dr Lustig specifically said that different people respond to different things, including those who have a genetic predisposition that makes fats problematic. The glucometer seems a good route to go, as most of us can’t get tested by Dr Lustig or similar. Here in the UK it’s impossible.

    William Davis refers to these anomalies in his latest blog post:

    http://heartscanblog.blogspot.com/2011/01/genetic-incompatibility.html

    Nina

    • http://www.livinlavidalowcarb.com Jimmy Moore

      RIGHT!

  • Olivia

    The mp3 download says file not found
    Error: 404 Not Found
    There was a problem processing your request. This is an uncommon error and should be reported to support@libsynpro.com. Please provide as much detail as possible which brought you to this page.
    Details:
    Sorry, we couldn’t find the file you are requesting
    Please check the referring URL
    Attempting to load:
    http://traffic.libsyn.com/llvlcshow/429_llvlc429-robert-lustig.mp3
    Previous URL:
    http://livinlavidalowcarb.com/blog/the-llvlc-show-episode-429-%e2%80%98encore-week%e2%80%99-2011-interview-with-dr-robert-lustig/9648

    • http://www.livinlavidalowcarb.com Jimmy Moore

      Try it again, Olivia! I just put the correct mp3 link in the post:

      Download the mp3

  • Peter Silverman

    Some low carb views on safe carbs:

    William Davis: Take your blood sugar and see how different carbs affect you.
    Robert Ludwig: whole wheat and brown rice are good because they are absorbed more slowly.
    Paul Jaminet: white rice is better than brown rice because it has fewer toxins.
    Stephan Guyenet: Potatoes are good, too.

    Wow, imagine a podcast where these guys discuss together the pro’s and cons of each view.

    • http://www.livinlavidalowcarb.com Jimmy Moore

      One more for the discussion: Gary Taubes who says ALL carbs are insulinogenic.

  • Matt Brody

    I thought the fiber discussion was interesting. He twice said that fiber should come in its intact form, not from cereal grains. I loved that – fiber as a natural part of its housing food, not fiber for fiber’s sake and certainly not bowls of twig cereal. So to hit his 50g fiber you’re ensuring a high fibrous vegetable intake, which is possibly realistic though a bit of a stretch for me. 1.5c of cooked broccoli has 15g of fiber. I suspect he doesn’t shy away from beans which would really be needed to get fiber where he suggests.

  • J W Anderson

    The arguments about glucose/no glucose in diet will eventually be settled. Fructose is indeed the major health culprit as far as metabolic syndrome; that is beyond question. Lustig has really put the scientific stake through the heart of that issue. What he, and most of the “low carb” community, is missing are the pieces about the sirtuin genes (our longevity genes), the ability of fructose to damage DNA, indeed any protein or lipid, and about glycations.

    Fructose is a very strong glycation agent, on the order of 6-15 times stronger than glucose. It is so powerful that it can cleave proteins, including DNA. As such, it may be a teratogen, a cancer promoter and an aging inducer.

    Glycations occur when a sugar bonds to a protein or lipid molecule without the controlling action of an enzyme. All sugars that are absorbed into the blood stream form glycations. These sugars are: Glucose, Fructose and Galactose (half of the disaccharide, lactose or milk sugar). Glycations, once formed, then proceed on through a chain of intermediate glycation products to Advanced Glycation End Products (AGEs). Most AGEs are damaging. Reactive Oxidation Species (ROS) are generated as the intermediate products progress toward AGEs. AGEs promote inflammation and may even catalyze further ROS production. AGEs appear to be one of the primary causes of aging and are lifetime accumulative.

    Teratogens are agents that cause birth defects. Once you know fructose can cleave DNA or glycate DNA and that human sperm metabolize fructose it’s easy to understand the opportunity fructose has for mischief with reproduction. Glucose can also cause glycation, but probably cannot cleave, DNA. Glycation of DNA may block the functionality of the genes by preventing replication of that area of the chromosome.

    Cancer cells have particular mutations that turn off apoptosis (normal cell death mechanism) and normal ATP metabolism. By cleaving or glycating DNA, sugars may promote cancer genesis. Also, cancer cells feed only on sugars in an anaerobic mode. Glucose has long been known to be a cancer metabolite and recently fructose has been found to have an independent, unregulated metabolic pathway in some cancers that may greatly increase cell proliferation rates.

    Sirtuins, very recently discovered, when turned on, slow the cellular clock, minimizing DNA “drift” and increase immune system function and repair mechanisms. Currently optimal “turn on” of SIRT-1 is thought to increase life span by 30-70%. Calorie restriction, known for over 70 years, is known to activate SIRT-1. It now appears that an optimal (primal) diet can do the same without calorie restriction. This is outlined in “Primal Body-Primal Mind” by Nora Gedgaudas. I recommend everyone read this book AND understand it. It’s not “just another” diet book. As far as I know, this is the first book to propose, from scientific principles, an optimal human diet. It is indeed a low carb, high fat diet with significant limitation of proteins as well, which is the unique feature.

    As far as I know, Johnson and Lustig are not aware of, or not yet recognizing, the issues with AGEs, glycations, protein cleavage and the sirtuins. I think Harris is probably not there yet, either. And, I haven’t even started on the mental health and neuropathies sugars cause. Taubes seems to be partly the way there. I’m sure Johnson and Lustig, they are really bright guys, will come along toward a very low glucose-forming diet when they get the info and the understanding.

    Best regards, Joe.