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ATLCX (Episode 31): Dr. Colin Champ | Ketogenic Diets And Cancer

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In Episode 31 of “Jimmy Moore Presents: Ask The Low-Carb Experts,” we take on a subject matter that will undoubtedly be the wave of the future in the coming years regarding how we treat cancer patients. Philadelphia physician Dr. Colin Champ from the “Caveman Doctor” blog and the hit iTunes health podcast “Relentless Roger & The Caveman Doctor” is currently involved in studying a topic that is very near and dear to his heart that happens to be what we discussed in this week’s ATLCX podcast. The hot topic we’ll be taking on in Episode 31 is “Ketogenic Diets & Cancer” which is gaining a lot of traction amongst researchers looking for nutritional solutions to this horrible disease.

Dr. Champ is completing his specialty training in radiation oncology and has a keen interest in the dietary effects of carbohydrate restriction on the prevention and treatment of cancer. The connection between our modern American diet, obesity and cancer has been quite remarkable, and Dr. Champ hopes that the work he is doing can help people fight all three. You may have already read his recent review article published in the scientific journal International Journal Of Breast Cancer entitled “Weight Gain, Metabolic Syndrome, and Breast Cancer Recurrence: Are Dietary Recommendations Supported by the Data?” and we’re seeing some truly incredible health benefits from carbohydrate-restricted diets for people dealing with this terrible disease.

Dr. Champ took on so many excellent questions about how ketogenic diets may play a role in the treatment of cancers. Listen in to hear what Dr. Colin Champ had to say about ketogenic diets and cancer in EPISODE 31 that aired LIVE on October 18, 2012.

Listen to Dr. Colin Champ share about “Ketogenic Diets And Cancer”:

  • There’s a BIG connection between ketogenic diets and cancer
  • We know that it is working to get rid of tumor cells
  • But we don’t know why it works…but it does work
  • We’re working backwards to figure out the details about why
  • One way it can work is by starving cancer cells of glucose
  • Otto Warburg said that cancer was caused by the uptake of glucose
  • Limiting glucose (low-carb or ketogenic) would lower blood glucose
  • Blood glucose is connected with survival in various studies
  • Deficient and defective mitochondria is possibly why glucose is used
  • With cancer cells whether there’s oxygen or not, glucose taken up
  • Ramp up mitochondria (by eating fat and some protein), work better
  • You can end up killing cancer cells if mitochondria is increased
  • Ketogenic diet is ramping up our defense against cancer
  • Our cells are being “constantly bombarded by free radicals”
  • Cancer cells have increased free radicals…we don’t know why
  • Cancer cells need more than just fuel to survive (hormones)
  • IGF-1 receptor and insulin play a HUGE role in cancer growth
  • Increasing the pathway that stops the growth, including…
  • Metformin, carbohydrate restriction and more
  • When in ketosis, chemotherapy tends to be a lot more effective
  • What the main difference is between low-carb and ketogenic diets
  • About 50g carbohydrates daily will have you “pump out the details”
  • But there are varying levels of carbohydrate to get into ketosis
  • That’s what I’ve done in my n=1 experiment of nutritional ketosis
  • You have to get to a certain level of blood ketones for it to work
  • Just going low-carb might be good for metabolic areas of cancer
  • When the outcomes are dependent on body structure, limiting insulin
  • Ketosis may be better, but it doesn’t necessarily require it
  • Dr. Eugene Fine’s study in October 2012 issue of Nutrition
  • Listen to Dr. Fine on The LLVLC Show podcast coming in Episode 628
  • The higher ketones were in Dr. Fine’s study, the lower the insulin
  • Metabolic derangement may mean the percentage of change matters most
  • What would happen if absolute values of blood ketones were over 2.0?
  • We don’t know the threshold of what’s best for treating cancer
  • It’s probably different for everyone, will take a very large study
  • Brain tumors get most of the attention with ketogenic diets
  • It’s easiest to get ketone bodies into the brain tumors
  • Pancreatic and lung cancer is also a very new area of study
  • Dr. Champ’s recent breast cancer and ketogenic diet review paper
  • They looked through the risk factors of non-cancer patients, too
  • Dr. Jeff Volek’s 2005 study of low-carb diets and metabolic syndrome
  • Controversy over carbohydrate restriction vs. calorie restriction
  • My interview with Dr. Thomas Seyfried in Episode 302 of The LLVLC Show
  • Dr. Seyfried is pushing the field, but it’s low-carb making changes
  • Some of these pathways are totally connected to carbohydrates
  • When cancer patients eat ketogenic, calorie restriction is natural
  • If you can get a bigger bang for your buck, why not cut the carbs?
  • Many calorie restriction studies were all about lowering carbs
  • Decreased tumor growth comes from less carbs and eating more fat
  • What if a cancer patient has had their gall bladder removed?
  • Go see a GI specialist to see how you can tolerate ketogenic diet
  • It’s very individualized and there are things that can be done
  • Christine had gall bladder out in 2008, adjusted to fat in 1 year
  • If you have endocrine issues, then you need to deal with those first
  • Low-carb can certainly put you back on the right path to success
  • The BRCA gene and the impact on cancer risk
  • Lowering circulating insulin, glucose and fat is ideal
  • Being as metabolically fit as possible will help get you there
  • No evidence that low-carb diets will help BRCA1 and BRCA2
  • It can’t hurt to do low-carb because “throwing down carbs” not good
  • How can we shake the “quack” label with ketogenic diets and cancer
  • Craig Thompson’s YouTube video “Why We All Don’t Get Cancer”:

    https://www.youtube.com/watch?v=WUlE1VHGA40

  • Fat doesn’t cause cancer, but sugar most certainly contributes
  • The future of cancer research will be seen as metabolic disease
  • Right now cancer is only looked at as a genetic disease
  • In the cancer world, you look for a drug that will fix the problem
  • Cancer cells take in glucose and LDL cholesterol
  • When you restrict carbs, both the glucose and fat stops going in
  • The companies that could stand to benefit from ketogenic research
  • The ketone products right now are “subpar” and companies clueless
  • Abbott (Precision Xtra) didn’t care about low-carbers testing
  • We don’t have any data supporting ketogenic diets and ovarian cancer
  • We’re not saying replacing traditional cancer care, supplementing
  • If going ketogenic causes “major anxiety” then may not want to do it
  • There is animal data showing ketogenic makes chemo work better
  • Fatty liver is “resolved” by eating a low-carb ketogenic diet
  • Brain tumor cells can raise cortisol which raises blood sugar
  • This is why a ketogenic diet may be good for brain cancer patients
  • Glutomate is an issue to get the blood glucose down
  • Cancer is a personal subject and people may not vocalize concerns
  • What he’s currently working on with ketogenic diets and cancer
  • His next paper will examine calorie restriction (carb restriction)
  • It will be a manual on doing IF and ketogenic diet for cancer
  • Average blood glucose in his patients is extremely high
  • It’s no coincidence 10 different diseases improved with low-carb
  • The ketogenic diet right now is still “experimental” for cancer
  • Looking forward to sharing my interview with Dr. Eugene Fine

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    There are five ways you can listen to Episode 31:

    1. LISTEN LIVE ON THURSDAY NIGHTS AT 7PM ET by calling (712) 432-0900 or on Skype at “freeconferencing.7124320900″–whether you call or Skype, be sure to use the access code “848908.” You can listen and even participate on the topic discussion by asking your questions directly to the featured expert.

    2. Listen at the iTunes page for the podcast:

    3. Listen and comment about the show at the official web site for the podcast:

    4. Download the MP3 file of Episode 31 [61:11m]:

    5. Listen on the Stitcher app–NO DOWNLOADING!

    If you cannot join us LIVE on the podcast on Thursday nights at 7PM ET, then you can still ask your questions of the expert guests in two ways. First, you can visit AskTheLowCarbExperts.com and fill out the form along the right-hand side of the page under “Submit Your Question” to input your name, e-mail address, the name of the expert you want to ask, and your question for them. These questions will be asked LIVE on the show airing on Thursdays. Or, for your convenience we have set up a way for you to e-mail us your questions directly to AskTheLowCarbExperts@gmail.com. Be sure to include your name, the name of the expert you want to ask your question to in the subject line, and your question on the specific topic of discussion. This is a golden opportunity for you to tap directly into the wealth of knowledge and experience on all things related to healthy low-carb living featuring the best and brightest experts in the realm of health!

    What did you think about what you heard from Dr. Colin Champ regarding the topic “Ketogenic Diets And Cancer?” Give us your feedback about it in the show notes section of Episode 31. Coming up next week LIVE in EPISODE 32 on October 25, 2012 at 7PM ET we’ll be pleased to welcome a heart surgeon named Dr. Steven Gundry to take on an interesting topic for those of us who are livin’ la vida low-carb–”High-Fat Diets: Good vs. Bad.” I had Dr. Gundry on “The Livin’ La Vida Low-Carb Show” in Episode 179 and 180 back in 2008 (definitely one of my favorite interviews from the early days) discussing his book Dr. Gundry’s Diet Evolution. He knows just a thing or two about healthy fats and how they respond inside your body as well as the ones that are not-so-healthy. Start getting me your questions NOW regarding good fats vs. bad fats for me to ask Dr. Steven Gundry by e-mailing them to AskTheLowCarbExperts@gmail.com no later than 3PM ET on the date the podcast airs. You can also ask your question LIVE on my show by calling (712) 432-0900 or Skype the show for FREE by calling the username freeconferencing.7124320900. Whether you call or Skype, be sure to use the access code 848908. Listen LIVE and leave us a review at iTunes if you like what you hear. This is your chance to interact with the best nutritional health experts in the world, so don’t be bashful.

    Here are the upcoming experts and topics we’ll be covering on #ATLCX:

    EPISODE 33: November 1, 2012 | Dr. Peter Attia | “Finding The Diet That’s Right For You”

    NO PODCASTS 11-2-12 through 1-9-13

    EPISODE 34: January 10, 2013 | Dr. Stephan Guyenet | “Obesity And The Metabolic Syndrome: How Do They Develop And Why Are They So Hard To Reverse?”

    Spread the word about this podcast: PLEASE REVIEW THE SHOW ON ITUNES!

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